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Mikio Watanabe Selected Research

Hashimoto Disease (Thyroiditis, Hashimoto)

5/2020Gene polymorphisms of VEGF and VEGFR2 are associated with the severity of Hashimoto's disease and the intractability of Graves' disease, respectively.
8/2017Association of IL-10-Regulating MicroRNAs in Peripheral Blood Mononuclear Cells with the Pathogenesis of Autoimmune Thyroid Disease.
5/2017Intraindividual variation of microRNA expression levels in plasma and peripheral blood mononuclear cells and the associations of these levels with the pathogenesis of autoimmune thyroid diseases.
1/2017TSHR Gene Polymorphisms in the Enhancer Regions Are Most Strongly Associated with the Development of Graves' Disease, Especially Intractable Disease, and of Hashimoto's Disease.
4/2016Increases of microRNA let-7e in peripheral blood mononuclear cells in Hashimoto's disease.
2/2015The relationship between skewed X chromosome inactivation and the prognosis of Graves' and Hashimoto's diseases.
10/2013IL-10 -592A/C polymorphism is associated with severity of Hashimoto's disease.
3/2012Functional polymorphisms in TBX21 and HLX are associated with development and prognosis of Graves' disease.
5/2009Increases of the Th1/Th2 cell ratio in severe Hashimoto's disease and in the proportion of Th17 cells in intractable Graves' disease.
3/2008The -590CC genotype in the IL4 gene as a strong predictive factor for the development of hypothyroidism in Hashimoto disease.
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Mikio Watanabe Research Topics

Disease

21Thyroid Diseases (Thyroid Disease)
11/2021 - 09/2002
16Hashimoto Disease (Thyroiditis, Hashimoto)
05/2020 - 09/2002
14Graves Disease (Basedow Disease)
05/2020 - 04/2003
3Hypothyroidism
05/2009 - 09/2002
2Inflammation (Inflammations)
08/2017 - 01/2016
2Autoimmune Diseases (Autoimmune Disease)
08/2017 - 01/2016
2Carcinoma (Carcinomatosis)
04/2013 - 07/2009
2Goiter
02/2013 - 12/2007
2Infections
01/2009 - 05/2003
1Hypoxia (Hypoxemia)
01/2022
1Thyroiditis
11/2021
1Lymphoma (Lymphomas)
10/2020
1T-Cell Lymphoma (Lymphoma, T Cell)
10/2020
1Pathologic Processes
04/2016
1Immunoglobulin G4-Related Disease
10/2013
1Organophosphate Poisoning
02/2013
1Thyroid Nodule (Nodule, Thyroid)
01/2012
1Pre-Eclampsia (Preeclampsia)
07/2010
1Neoplasm Metastasis (Metastasis)
09/2009
1Colorectal Neoplasms (Colorectal Cancer)
09/2009
1Neoplasms (Cancer)
07/2009
1Aneurysm (Aneurysms)
11/2006
1Dehydration (Water Stress)
10/2006
1Hemolysis
12/2005
1Coronary Artery Disease (Coronary Atherosclerosis)
06/2005
1Atherosclerosis
06/2005
1Mumps
05/2003
1Rubella (German Measles)
05/2003
1Chickenpox
05/2003
1Virus Diseases (Viral Diseases)
05/2003
1Measles
05/2003

Drug/Important Bio-Agent (IBA)

4DNA (Deoxyribonucleic Acid)IBA
10/2020 - 03/2012
4Interleukin-10 (Interleukin 10)IBA
08/2017 - 03/2004
4Thyroxine (Levothyroxine)FDA LinkGeneric
02/2013 - 09/2002
3MicroRNAs (MicroRNA)IBA
08/2017 - 04/2016
3AntibodiesIBA
01/2017 - 05/2003
3Immunoglobulin G (IgG)IBA
10/2013 - 04/2003
3Messenger RNA (mRNA)IBA
04/2013 - 07/2009
3Interleukin-4 (Interleukin 4)IBA
05/2009 - 03/2004
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2022 - 05/2020
2Iodide Peroxidase (Deiodinase)IBA
07/2018 - 10/2017
2InterleukinsIBA
08/2017 - 12/2007
2CytokinesIBA
10/2013 - 03/2004
2thyrotropin-binding inhibitory immunoglobulinIBA
02/2013 - 06/2004
2Antithyroid Agents (Antithyroid Drugs)IBA
12/2007 - 06/2004
2Immunoglobulins (Immunoglobulin)IBA
12/2007 - 04/2003
2EnzymesIBA
03/2004 - 04/2003
1Transcription Factors (Transcription Factor)IBA
01/2022
1ErythropoietinFDA Link
01/2022
1Facilitative Glucose Transport Proteins (Glucose Transporter)IBA
01/2022
1Retinoic Acid 4-Hydroxylase (CYP26B1)IBA
11/2021
1Vitamin A (Retinol)FDA LinkGeneric
11/2021
1LigandsIBA
11/2021
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
05/2020
1Proteins (Proteins, Gene)FDA Link
02/2020
1Interleukin-6 (Interleukin 6)IBA
11/2019
1ThyroglobulinFDA Link
09/2017
1Interleukin-12 (IL 12)IBA
07/2017
1Interleukin-18 (Interleukin 18)IBA
07/2017
1Toll-Like Receptors (Toll-Like Receptor)IBA
05/2017
1Biomarkers (Surrogate Marker)IBA
05/2017
1Type II Tumor Necrosis Factor ReceptorsIBA
10/2016
1Type I Tumor Necrosis Factor ReceptorsIBA
10/2016
1Interleukin-8 (Interleukin 8)IBA
01/2016
1Chemotactic FactorsIBA
01/2016
1Histone Deacetylases (Histone Deacetylase)IBA
01/2016
1NAD (NADH)IBA
01/2016
1ChemokinesIBA
01/2016
1Chemokine CCL5IBA
01/2016
1Interleukin-16 (Interleukin 16)IBA
01/2016
1Sirtuin 1IBA
01/2016
1pralidoxime (Protopam Chloride)FDA Link
02/2013
1SaltsIBA
02/2013
1CreatinineIBA
07/2010
1AntigensIBA
09/2009
1Carcinoembryonic AntigenIBA
09/2009
1Differentiation AntigensIBA
07/2009
1NestinIBA
07/2009
1Long-Acting Thyroid Stimulator (LATS)IBA
05/2009
1Indicators and Reagents (Reagents)IBA
01/2009
1Pharmaceutical PreparationsIBA
12/2007
1Polytetrafluoroethylene (Teflon)FDA Link
11/2006
1Lactic Acid (Lactate)FDA LinkGeneric
10/2006
1poly(lactide) (polylactic acid)IBA
10/2006
1Interferon-gamma (Interferon, gamma)IBA
08/2006
1anti-thyroglobulinIBA
08/2006
1PotassiumIBA
12/2005
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
06/2005
1Pravastatin (Pravachol)FDA LinkGeneric
06/2005
1Fas Ligand Protein (Fas Ligand)IBA
10/2004
1Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
06/2004
1VaccinesIBA
05/2003
1Immunoglobulin M (IgM)IBA
04/2003
1Immunoglobulin A (IgA)IBA
04/2003
1AutoantibodiesIBA
09/2002

Therapy/Procedure

1Surgical Instruments (Clip)
11/2006
1Coronary Artery Bypass (Coronary Artery Bypass Surgery)
06/2005